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Apexbio Technology LLC (+)-Ketoconazole 142128-59-4 10mg
Supplier: Apexbio Technology LLC B124010
( )-Ketoconazole (CAS 142128-59-4) is a small-molecule inhibitor targeting cytochrome P450 enzymes primarily CYP3A4 and P450c17 (CYP17A1) It is designed to inhibit these enzymes thereby blocking steroidogenesis pathways and reducing androgen biosynthesis ( )-Ketoconazole exerts its biological activity primarily through inhibition of CYP3A4 and CYP17A1 In in vitro studies ( )-Ketoconazole demonstrates inhibitory activity with reported IC50 values in the low nanomolar to submicromolar range Based on these pharmacological properties ( )-Ketoconazole holds research potential in studying steroid hormone biosynthesis pathways and the biological functions regulated by cytochrome P450 enzyme activity particularly in investigations involving androgen-dependent cell models and related endocrine mechanisms
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