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Apexbio Technology LLC Ketoconazole 65277-42-1 500mg
Supplier: Apexbio Technology LLC A4316500
Ketoconazole (65277-42-1) is a small-molecule inhibitor targeting cytochrome P450-dependent enzymes including cyclosporine oxidase and testosterone 6 -hydroxylase It is designed to inhibit these catalytic activities thereby modulating the oxidative metabolism of clinically relevant substrates Ketoconazole exerts its biological activity primarily through inhibition of cytochrome P450-mediated pathways In in vitro studies ketoconazole demonstrates inhibitory activity with an IC50 of approximately 0 19 mM for cyclosporine oxidase and about 0 22 mM for testosterone 6 -hydroxylase Based on these pharmacological properties ketoconazole holds research potential in studies of drug-drug interactions hepatic enzyme induction and metabolic profiling assays
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