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Medchemexpress LLC KL-11743 | 1369452-53-8 | 99.4% | C30H30N6O3 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY145597100MG

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KL-11743 is a potent, orally active, and glucose-competitive inhibitor of class I glucose transporters (GLUT1, GLUT2, GLUT3, and GLUT4), with IC50s of 115, 137, 90, and 68 nM respectively. It specifically blocks glucose metabolism and can synergize with electron transport inhibitors to induce cell death, additionally inducing cellular disulfidptosis by forming disulfide bonds in actin cytoskeletal proteins.

  • Potent, orally active glucose-competitive inhibitor
  • Inhibits class I glucose transporters (GLUT1, GLUT2, GLUT3, GLUT4)
  • Blocks glucose metabolism
  • Synergizes with electron transport inhibitors to induce cell death
  • Induces cellular disulfidptosis

Catalog No. 50-003-55226


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