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Selleck Chemical LLC KN-62 5mg 127191-97-3
Supplier: Selleck Chemical LLC S74225MG
KN-62 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.9 ?M; also a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM). It is selective for CaMKII relative to PKA, PKC and MLCK, but inhibits CaMKI and CaMKIV equally well, The Ki value of KN-62 for CaMK V is 0.8 ?M. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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