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Abcam KN-62, CaM kinase II inhibitor. P2 x 7 antagonist., 1MG
Supplier: Abcam AB1204211MG
MW 721.8 Da, Purity >98%. Cell-permeable, reversible and selective inhibitor of CaM kinase II (IC50 = 500 nM). Interacts with the calmodulin binding site of the enzyme. At higher concentrations reported to inhibit GSK3β, PRAK and MAPKAP-K2. Also potent non-competitive antagonist at the P2X7 receptor (IC50 = 15 nM).
The product is subject to the following: Abcam Restricted Use Statement
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