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ABclonal Technology KO Validated IRF3 Rabbit mAb

Supplier: ABclonal Technology A2727220UL
This gene encodes a member of the interferon regulatory transcription factor (IRF) family The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP This complex translocates to the nucleus and activates the transcription of interferons alpha and beta as well as other interferon-induced genes The protein plays an important role in the innate immune response against DNA and RNA viruses Mutations in this gene are associated with Encephalopathy acute infection-induced herpes-specific 7
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