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Medchemexpress LLC KRAS G12D inhibitor 1 | 2621928-43-4 | MFCD00237621 | 98.5% | 582.64 g/mol | C33H32F2N6O2 | 5 MG
SDP

Supplier:  Medchemexpress LLC HY1348115MG

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KRAS G12D inhibitor 1 is a potent, selective small-molecule inhibitor of the oncogenic KRAS G12D mutant for preclinical research. It demonstrates subnanomolar biochemical potency and cellular activity and is supplied as solid material and as a DMSO stock for laboratory use.

  • Potent inhibition of KRAS G12D (IC50 = 0.4 nM in biochemical assay).
  • Inhibits KRAS G12D-mediated ERK phosphorylation (IC50 = 0.8 nM in cellular assay).
  • Suitable for preclinical research of cancers with KRAS G12D mutations.
  • Available as solid (1 mg, 5 mg, 10 mg) and 10 mM 1 mL DMSO stock.
  • Molecular formula C33H32F2N6O2; molecular weight 582.64 g/mol.
  • High purity (≈98.5%).

Catalog No. 50-002-22853


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