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Medchemexpress LLC KS100 | 2408477-54-1 | 99.6% | 564.09 | 25 MG
Supplier: Medchemexpress LLC 25MGHY146682
KS100 is a potent ALDH inhibitor with IC50 values of 230 nM for ALDH1A1, 1542 nM for ALDH2, and 193 nM for ALDH3A1. It demonstrates antiproliferative and anticancer effects with low toxicity, increasing ROS activity, lipid peroxidation, and toxic aldehyde accumulation. It also induces apoptosis and cell cycle arrest at the G2/M phase.
- Potent ALDH inhibitor targeting ALDH1A1, ALDH2, and ALDH3A1
- Exhibits antiproliferative and anticancer effects
- Low toxicity
- Increases ROS activity, lipid peroxidation, and toxic aldehyde accumulation
- Induces apoptosis and cell cycle arrest at the G2/M phase
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