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Medchemexpress LLC L-371,257 | 162042-44-6 | 99.3% | 507.58 | 10 MM / 1 ML
SDP

Supplier:  Medchemexpress LLC HY1501010MM/1ML

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L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective, and competitive antagonist of the oxytocin receptor (pA2=8.4). It exhibits high affinity at both the oxytocin receptor (Ki=19 nM) and vasopressin V1a receptor (Ki=3.7 nM).

  • Orally bioavailable
  • Non-blood-brain barrier penetrant
  • Selective and competitive antagonist of the oxytocin receptor
  • High affinity at oxytocin receptor (Ki=19 nM)
  • High affinity at vasopressin V1a receptor (Ki=3.7 nM)
  • Appears as a white to off-white solid
  • Storage as powder: -20°C for 3 years, 4°C for 2 years
  • Storage in solvent: -80°C for 6 months, -20°C for 1 month
  • Soluble in DMSO at 8.33 mg/mL (16.41 mM)

Catalog No. 50-003-60490


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