Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC L-692429 (mk-0751) | 145455-23-8 | 99.9% | 509.60 | 5 G
Supplier: Medchemexpress LLC HY1095710MM/1ML
L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidyl growth hormone secretagogue (GHS) agonist that binds to G protein-coupled receptors with a Ki of 63 nM. This product is for research use only. It stimulates intracellular calcium release, inositol phosphate (IP) turnover, cAMP-responsive element binding protein (CREB) activity, serum-responsive element activity, and bioluminescence resonance energy transfer (BRET) activity. L-756867 inhibits L-692429-stimulated GH secretion in anesthetized rats.
- Binds to G protein-coupled receptors
- Stimulates intracellular calcium release (EC50: 26 nM)
- Stimulates IP turnover (EC50: 47 nM)
- Stimulates CREB activity (EC50: 60 nM)
- Stimulates SRE activity (EC50: 63 nM)
- Stimulates BRET activity (EC50: 58 nM)
- Activates MAPK pathway in hela-T4 cells
- Inhibits GH secretion in anesthetized wistar rats
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?