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Apexbio Technology LLC L-798,106 244101-02-8 50mg
Supplier: Apexbio Technology LLC B737150
L-798 106 (CAS 244101-02-8) is a highly selective antagonist of the prostaglandin E2 (EP3) receptor Binding studies demonstrate a strong affinity for the EP3 receptor with a Ki of 0 3 nM while showing substantially reduced affinity for EP1 ( 5000 nM) EP2 ( 5000 nM) and EP4 (916 nM) receptors By selectively inhibiting EP3 receptor-mediated signaling L-798 106 is utilized to investigate the physiological and pathological roles of EP3 in various disease models and serves as a molecular tool in the preclinical evaluation of EP3-targeted therapeutic strategies
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