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Medchemexpress LLC L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methyl-d3-amino]benzoyl]- | 432545-63-6 | ≥99.0% | C20H19D3N8O5 | 50MG
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Supplier:  Medchemexpress LLC HY14519S150MG

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Methotrexate-d3 (Amethopterin-d3) is a deuterium labeled form of Methotrexate, an antimetabolite and antifolate agent. It inhibits dihydrofolate reductase, preventing folic acid conversion and inhibiting DNA synthesis. It also acts as an immunosuppressant and antineoplastic agent, used in research for conditions like rheumatoid arthritis and various cancers.

  • Used as a tracer.
  • Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
  • Incorporates stable heavy isotopes into drug molecules for quantitation during drug development.
  • Potential to affect the pharmacokinetic and metabolic profiles of drugs through deuteration.

Catalog No. 50-003-56520


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