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Medchemexpress LLC γ-L-Glutamyl-L-alanine | 5875-41-2 | 98.0% | 218.21 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY11217150MG

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γ-L-Glutamyl-L-alanine (γ-Glu-Ala) is a proteolytic breakdown product of larger proteins, composed of gamma-glutamate and alanine. It serves as a natural substrate for γ-Glutamylcyclotransferase and acts as a positive modulator of calcium-sensing receptor (CaR) function.

  • Shows potency for Ca2+i mobilization in CaR (calcium-sensing receptor)-expressing HEK-293 cells, with an EC50 of 4.8 μM.
  • Shows potency for Ca2+i mobilization in human parathyroid cells with an EC50 of 13.9 μM.
  • Suppresses PTH secretion from normal human parathyroid cells at 20 μM.
  • Is a substrate for glutaminase B.

Catalog No. 50-004-35922


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