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Cayman Chemical L-KynurenIn-d4 500ug

Supplier: Cayman Chemical 36307500 UG
An isocoumarin with diverse biological activities inhibits increases in TNF-a IL-6 and IL-1B levels induced by LPS Pam3CSK4 or FSL-1 but not poly(IC) or ODN1668 in primary mouse macrophages at 100 UM reduces HIV-1 p24 antigen levels in the culture supernatant of human PBMCs infected with HIV-1 at 1-10 UM induces apoptosis cell cycle arrest at the G2/M phase and production of ROS in SH-SY5Y cells at 10 UM protects mice from lethal endotoxin shock at 3 and 9 mg/kg
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