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Medchemexpress LLC L-phenylalaninamide, N-[(2R,4R,5S)-5-[[(1,1-dimethylethoxy)carbonyl]amino]-4-hydroxy-1-oxo-6-phenyl- | 292632-98-5 | 99.5% | 672.85 | 25 MG
SDP

Supplier:  Medchemexpress LLC 25MGHY19369

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L-685458 is a potent transition state analog (TSA) γ-secretase inhibitor (GSI) that inhibits amyloid β-protein precursor γ-secretase activity with an IC50 of 17 nM. It demonstrates high selectivity compared to other aspartyl proteases and inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100. This compound is suitable for research related to Alzheimer's disease (AD) and various cancers.

  • Potent transition state analog γ-secretase inhibitor
  • High selectivity against other aspartyl proteases
  • Inhibits γ-secretase-mediated cleavage of APP-C99 and Notch-100
  • Useful for Alzheimer's disease and cancer research
  • Purity of 99.48%
  • Appearance as a white to off-white solid

Catalog No. 50-003-85557


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