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Medchemexpress LLC Lartesertib | 2495096-26-7 | C23H21FN6O3 | 1 MG
Supplier: Medchemexpress LLC HY1506171MG
Lartesertib (M4076) is a potent inhibitor of the serine/threonine protein kinase ATM. It has demonstrated the ability to inhibit the growth of various hematopoietic cell lines. When used in combination with the ATR inhibitor Tuvusertib (HY-111451), Lartesertib can induce tumor cell death, activate immune signaling pathways, and exhibit anti-tumor activity. It also alters the tumor microenvironment by upregulating PD-L1.
- Potent inhibitor of ATM protein kinase
- Inhibits growth of multiple hematopoietic cell lines
- Induces tumor cell death when combined with Tuvusertib
- Activates immune signaling pathways
- Demonstrates anti-tumor activity
- Upregulates PD-L1 on immune and tumor cells
- Alters the tumor microenvironment
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