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Medchemexpress LLC Lartesertib | 2495096-26-7 | C23H21FN6O3 | 5 MG
Supplier: Medchemexpress LLC HY1506175MG
Lartesertib (M4076) is a highly potent inhibitor of the serine/threonine protein kinase ATM. It exhibits potential chemo-/radio-sensitizing and antineoplastic activities by inhibiting ATM kinase activity and signaling. This action prevents DNA damage checkpoint activation, disrupts DNA damage repair, and induces apoptosis in tumor cells.
- Highly potent inhibitor of ATM kinase.
- Inhibits the growth of various hematopoietic cell lines.
- Promotes tumor cell death when combined with ATR inhibitor.
- Activates the immune signaling pathway.
- Exhibits anti-tumor activity.
- Sensitizes tumor cells to chemo- and radiotherapy.
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