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Medchemexpress LLC Latanoprost acid | 41639-83-2 | 95.1% | 390.51 | 10 MG
SDP

Supplier:  Medchemexpress LLC HY113756A10MG

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Latanoprost acid, an analog of prostaglandin (PG) F2α, is a selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. It inhibits RANKL-induced osteoclastogenesis and function by inhibiting the ERK, AKT, JNK, and p38 cascade, followed by the c-fos/NFATc1 pathway. Latanoprost acid is also a medication used to lower pressure inside the eyes.

  • Selective prostanoid receptor (FP) agonist.
  • Activates the FP-PG receptor.
  • Inhibits RANKL-induced osteoclastogenesis and function.
  • Lowers pressure inside the eyes.
  • Inhibits ERK, AKT, JNK, and p38 cascade.
  • Reduces protein expressions of c-fos and NFATc1 in bone marrow-derived macrophages cells (BMMs).
  • Significantly inhibits mature osteoclast formation.
  • Notably prevents LPS-induced bone destruction in 8-week-old C57BL/6J mice.

Catalog No. 50-004-36400


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