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Medchemexpress LLC Latanoprost acid | 41639-83-2 | 95.1% | 390.51 | 50 MG
Supplier: Medchemexpress LLC HY113756A50MG
Latanoprost acid, an analog of prostaglandin (PG) F2α, is a selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. It inhibits RANKL-induced osteoclastogenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, followed by the c-fos/NFATc1 pathway. Latanoprost acid is a medication used to lower pressure inside the eyes.
- Selective prostanoid receptor (FP) agonist
- Specifically activates the FP-PG receptor
- Inhibits RANKL-induced osteoclastogenesis and function
- Inhibits ERK, AKT, JNK, and p38 cascade
- Inhibits the c-fos/NFATc1 pathway
- Lowers pressure inside the eyes
- Reduces the protein expressions of c-fos and NFATc1 in vitro
- Significantly inhibits mature osteoclast formation in vitro
- Notably prevents LPS-induced bone destruction in vivo
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