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Selleck Chemical LLC Lazertinib S8724-25MG

Supplier: Selleck Chemical LLC S872425MG
Lazertinib (YH25448 GNS-1480) is a potent highly mutant-selective and irreversible EGFR-TKI with IC50 values of 1 7 nM 2 nM 5 nM 20 6 nM and 76 nM for Del19/T790M L858R/T790M Del19 L85R and Wild type EGFR respectively showing much higher IC50 values aganist ErbB2 and ErbB4
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