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Selleck Chemical LLC LDN-193189 S2618-1g
Supplier: Selleck Chemical LLC S26181G
LDN-193189 (DM3189) is a selective BMP signaling inhibitor inhibits the ALK1 ALK2 ALK3 and ALK6 with IC50s of 0 8 nM 0 8 nM 5 3 nM and 16 7 nM in the kinase assay respectively LDN-193189 inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50s of 5 nM and 30 nM in C2C12 cells respectively exhibits 200-fold selectivity for BMP versus TGF- For cell testing the water-soluble S7507 LDN-193189 2HCl is recommended This product has poor solubility animal experiments are available cell experiments please choose carefully
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