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Medchemexpress LLC Letermovir | 917389-32-3 | C29H28F4N4O4 | 1 ML
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Supplier:  Medchemexpress LLC HY1523310MM/1ML

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Letermovir (AIC246) is a potent inhibitor of CMV that targets the viral terminase complex and remains active against viruses resistant to DNA polymerase inhibitors. It inhibits HCMV replication by interfering with the proper cleavage/packaging of HCMV progeny DNA, involving the viral gene product UL56.

  • Exhibits consistent antiviral efficacy and remarkable selectivity for human cytomegaloviruses.
  • Inhibits HCMV replication by interfering with proper cleavage/packaging of HCMV progeny DNA.
  • Superior potency compared to ganciclovir (GCV).
  • Additive antiviral effects when combined with anti-HCMV drugs.
  • Leads to a dose-dependent reduction of HCMV titer in mouse xenograft models.

Catalog No. 50-003-72079


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