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Medchemexpress LLC Leu-AMS | 288591-93-5 | 99.6% | 459.48 | 1 MG
Supplier: Medchemexpress LLC HY10890010MM/1ML
Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM. It inhibits the catalytic activity of LRS but does not affect leucine-induced mTORC1 activation. Leu-AMS exhibits cytotoxicity in cancer cells and normal cells and inhibits bacterial growth.
- Potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM.
- Inhibits the catalytic activity of LRS.
- Does not affect leucine-induced mTORC1 activation.
- Shows cytotoxicity in cancer cells and normal cells.
- Inhibits the growth of bacteria.
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