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AdipoGen Leupeptin Hemisulfate, 103476-89-7, MFCD00037012, 100 mg
Supplier: AdipoGen AGCP37000M100
MF: C20H38N6O4 . 0.5 H2SO4, MW: 426.6 . 49.0, ≥97%, Appearance: White to off-white powder. Potent, competitive and reversible cysteine, serine and threonine protease inhibitor. Inhibits calpain, kallikrein, trypsin, plasmin, papain and cathepsin B. Does not inhibit pepsin, elastase, renin, cathepsins A and D, thrombin or alpha-chymotrypsin. Used to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. Shown to inhibit activation-induced programmed cell death. Antioxidant and anti-inflammatory agent. Widely used as a protein purification tool to prevent proteases present in tissue samples from degrading the protein of interest.
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