Sigma Aldrich Fine Chemicals Biosciences Leupeptn mcrobal 90 HPL250MG

Supplier:  Sigma Aldrich Fine Chemicals Biosciences L2884250MG

Leupeptin or N-acetyl-L-leucyl-L-leucyl-L-argininal is a naturally occurring tripeptide that acts particularly as a serine protease inhibitor and as a cysteine protease inhibitor. Its mechanism of action involves structurally similar covalent binding reactionsbullnbspIn the active site of serine proteases leupeptin forms a covalent hemiacetal adduct between the aldehyde group of leupeptin and the hydroxyl group of a serine residue in the enzyme active site.bullnbspIn the active site of cysteine proteases the electrophilic (aldehyde) carbon of leupeptin forms a comparable bond with the sulfur atom of a cysteine residue in the enzyme active site.

Catalog No. 50-291-4238