Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. 5000386720

Medchemexpress LLC LGK974 (WNT974) | 1243244-14-5 | 99.9% | 396.44 | 100 MG
SDP

Supplier:  Medchemexpress LLC HY17545100MG

Encompass_Preferred

LGK974 (WNT974) is an orally bioavailable and specific Porcupine (PORCN) inhibitor with an IC50 of 0.1 nM. It is intended for research use only.

  • Target porcupine (PORCN)
  • Inhibits PORCN with an IC50 of 0.1 nM
  • Potently reduces Wnt-dependent AXIN2 mRNA levels in HN30 cells with an IC50 of 0.3 nM
  • Effectively displaces [3H]-GNF-1331 with an IC50 of 1 nM in the PORCN radioligand binding assay
  • Inhibits Wnt signaling and shows strong efficacy in rodent tumor models
  • Available as a solid, white to light brown
  • Store powder at -20°C for 3 years or 4°C for 2 years
  • Store in solvent at -80°C for 2 years or -20°C for 1 year

Catalog No. 50-003-86720


May include imposed supplier surcharges.
Add to Cart

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.