Apexbio Technology LLC Loratadine 79794-75-5 10mM (in 1mL DMSO)

Supplier:  Apexbio Technology LLC A29605.1

Loratadine is a selective peripheral antagonist targeting histamine H1 receptors (HH1R) exhibiting a binding affinity (Ki) of approximately 35 nM Through selective blockade of peripheral histamine receptors loratadine counteracts histamine-mediated allergic responses without central nervous system penetration thus eliminating typical central side effects As an orally bioavailable compound it is routinely employed in biomedical research to investigate allergic inflammation pathways histamine receptor modulation and peripheral antihistamine pharmacodynamics Loratadine serves as a reference tool in pharmacological studies evaluating allergic reactions receptor selectivity assays and H1 receptor-associated downstream signaling mechanisms

Catalog No. 50-000-63176