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Cayman Chemical Lovastatin, 75330-75-5, 10 mg
Supplier: Cayman Chemical 1001033810
Molecular Formula C24H36O5, Purity ≥98%, Formula Weight 404.5; A prodrug of lovastatin hydroxy acid; a potent and competitive inhibitor of HMG-CoA reductase (Kis = 1.4 and 0.6 nM for lovastatin and lovastatin hydroxy acid, respectively); reduces plasma cholesterol by 29% in dogs over a period of three weeks at a dose of 8 mg/kg/day; suppresses TNF-induced NF-B activation (IC50 ~ 15 M).
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