Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC Lurasidone (Hydrochloride) | 367514-88-3 | 99.65% | 529.14 | 500 MG
Supplier: Medchemexpress LLC 500MGHYB0032
Lurasidone (Hydrochloride) acts as an antagonist for dopamine D2 and 5-HT7 receptors, with IC50s of 1.68 nM and 0.495 nM, respectively. It also functions as a partial agonist for the 5-HT1A receptor, exhibiting an IC50 of 6.75 nM.
- Shows higher affinity for dopamine D2 and 5-HT2A receptors compared to other antipsychotics tested.
- Dose-dependently increases the DOPAC/dopamine ratio in both the frontal cortex and striatum, with a more pronounced effect on the frontal cortex at higher doses.
- Dose-dependently inhibits conditioned avoidance response (CAR) in rats.
- Dose-dependently inhibits TRY-induced forepaw clonic seizure and p-CAMP-induced hyperthermia.
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?