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Medchemexpress LLC Luteolin 7-diglucuronide | 96400-45-2 | 10 MG
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Supplier:  Medchemexpress LLC HYN726910MG

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Luteolin 7-diglucuronide is the main flavonoid isolated from *Aloysia triphylla* and *Verbena officinalis*. It presents as a yellow to brown solid and has demonstrated significant biological activities both in vitro and in vivo.

  • Inhibits protein tyrosine phosphatase 1B (PTP1B) activity with an IC50 of 2.10 μM.
  • Upregulates the phosphorylation of AMPK, inhibiting the activation of hepatic stellate cells.
  • Exhibits protective effects against Isoproterenol-induced myocardial injury and fibrosis in mouse models.
  • Reduces myocardial necrosis, granulation tissue formation, and inflammatory cell infiltration.
  • Inhibits the expression of NADPH oxidase subunits and ECM genes.

Catalog No. 50-004-17256


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