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Medchemexpress LLC Ly-2584702 tosylate salt | 1082949-68-5 | 99.5% | 617.62 | C28H27F4N7O3S | 500MG
SDP

Supplier:  Medchemexpress LLC HY12493A500MG

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LY-2584702 tosylate salt is a selective ATP-competitive inhibitor of p70S6K used for biochemical and cellular research into S6K signaling. It exhibits low-nanomolar potency in enzyme assays and reduces phosphorylation of S6 in cellular models. The compound is supplied as a light yellow solid and is typically prepared as a DMSO stock for in vitro studies.

  • Selective ATP-competitive inhibitor of p70S6K; p70S6K IC50 4 nM, S6K1 enzyme assay IC50 2 nM.
  • Inhibits cellular pS6 with effective concentrations around 100 nM; HCT116 pS6 IC50 0.1-0.24 μM.
  • Observed off-target activity against MSK2 and RSK at higher concentrations (58-176 nM).
  • High purity (99.5%) and light yellow solid appearance.
  • Molecular formula C28H27F4N7O3S; molecular weight 617.62 g/mol.
  • Stable when stored sealed away from moisture; in solution store at -80°C (1 year) or -20°C (6 months).
  • Soluble in DMSO; prepare a 10 mM stock solution for in vitro assays.

Catalog No. 50-002-38163


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