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Medchemexpress LLC LY-2584702 (tosylate salt) | 1082949-68-5 | 99.5% | 617.62 | 10 MG
SDP

Supplier:  Medchemexpress LLC 10MGHY12493A

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LY-2584702 tosylate salt is a selective ATP competitive inhibitor of p70S6K with an IC50 of 4 nM. In the S6K1 enzyme assay, the IC50 of LY-2584702 is 2 nM. It inhibits phosphorylation of the S6 ribosomal protein in HCT116 colon cancer cells and demonstrates significant single-agent efficacy in glioblastoma and colon carcinoma xenograft models.

  • Selective ATP competitive inhibitor of p70S6K.
  • Inhibits phosphorylation of the S6 ribosomal protein in HCT116 colon cancer cells.
  • Demonstrates significant single-agent efficacy in glioblastoma and colon carcinoma xenograft models.
  • Inhibits S6K activity in EOMA cells.
  • Inhibits proliferation of A549 and SK-MES-1 cells.

Catalog No. 50-003-65278


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