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Medchemexpress LLC LY223982 | 117423-74-2 | 99.7% | 502.56 | 1 ML
Supplier: Medchemexpress LLC HY11273710MM/1ML
LY223982 is a potent and specific inhibitor of the leukotriene B4 receptor. It effectively blocks the binding of [3H]LTB4 to its receptor with an IC50 of 13.2 nM. This compound also acts as a potent antagonist of human neutrophil aggregation induced by LTB4 and inhibits transient leukopenia in rabbits.
- Potent and specific inhibitor of leukotriene B4 receptor
- Inhibits [3H]LTB4 binding to LTB4 receptor (IC50: 13.2 nM)
- Antagonizes aggregation of human neutrophils by LTB4 (IC50: 100 nM)
- Inhibits transient leukopenia induced by LTB4 in rabbits (ED50: 3 mg/kg)
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