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Apexbio Technology LLC LY2608204 1234703-40-2 5mg
Supplier: Apexbio Technology LLC B21605
LY2608204 (CAS 1234703-40-2) is a small molecule activator of glucokinase (GK) enhancing its activity as indicated by an EC50 of 42 nM under low glucose conditions In the INS1-E rat insulinoma cell line LY2608204 stimulates glucose metabolism with an EC50 of 579 nM Preclinical studies have demonstrated that administration of LY2608204 leads to dose-dependent reductions in both fasting and postprandial blood glucose levels These properties make LY2608204 a valuable tool for investigating GK modulation and its effects on glucose homeostasis in metabolic disease research
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