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Medchemexpress LLC Ly294002 | 154447-36-6 | 307.34 | 200 MG
Supplier: Medchemexpress LLC 200MGHY10108
LY294002 is a broad-spectrum inhibitor of PI3K with IC50s of 0.5, 0.57, and 0.97 μM for PI3Kα, PI3Kδ, and PI3Kβ, respectively. It also inhibits CK2 with an IC50 of 98 nM. LY294002 acts as a competitive DNA-PK inhibitor, binding reversibly to the kinase domain of DNA-PK with an IC50 of 1.4 μM, and is also an apoptosis activator.
- Targets PI3K, Casein Kinase, DNA-PK
- Supports research in apoptosis, autophagy, infection, and cancer
- Has IC50 values for PI3Kα (0.5 μM), PI3Kδ (0.57 μM), PI3Kβ (0.97 μM), CK2 (98 nM), and DNA-PK (1.4 μM)
- Acts as an apoptosis activator
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