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Medchemexpress LLC LY3522348 | 2568608-48-8 | 98.3% | 409.41 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14998750MG

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LY3522348 (KHK-IN-3) is an inhibitor of ketohexokinase (KHK), a rate-limiting enzyme and fructokinase involved in fructose metabolism. KHK catalyzes the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition in fructose metabolism leads to the accumulation of downstream intermediates, contributing to lipogenesis, gluconeogenesis, and oxidative phosphorylation.

  • KHK inhibitor.
  • Can be utilized in studies related to kidney disease.
  • Applicable in research concerning nonalcoholic steatohepatitis (NASH).
  • Useful in diabetes research.
  • Can be used to study heart failure.

Catalog No. 50-003-60483


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