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Medchemexpress LLC LY3522348 | 2568608-48-8 | 98.3% | 409.41 | 500 MG
SDP

Supplier:  Medchemexpress LLC HY149987500MG

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LY3522348 (KHK-IN-3) is a ketohexokinase (KHK) inhibitor. KHK is a rate-limiting enzyme and fructokinase involved in fructose metabolism, catalyzing the phosphorylation of fructose to fructose-1-phosphate (FIP) at the expense of ATP. The lack of feedback inhibition in fructose metabolism leads to the accumulation of downstream intermediates such as lipogenesis, gluconeogenesis, and oxidative phosphorylation.

  • Ketohexokinase (KHK) inhibitor
  • Can be used in the study of kidney disease
  • Can be used in the study of nonalcoholic steatohepatitis (NASH)
  • Can be used in the study of diabetes
  • Can be used in the study of heart failure

Catalog No. 50-003-61022


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