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Medchemexpress LLC m-PEG6-Amine | 184357-46-8 | ≥97.0% | 25 G
Supplier: Medchemexpress LLC 25GHY130408
m-PEG6-Amine is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It also functions as a cleavable ADC linker for the creation of antibody-drug conjugates (ADCs). PROTACs are designed to exploit the intracellular ubiquitin-proteasome system, selectively degrading target proteins by connecting an E3 ubiquitin ligase ligand to a target protein ligand via a linker. ADCs, on the other hand, consist of an antibody attached to a cytotoxin through an ADC linker.
- Functions as a PEG-based PROTAC linker
- Acts as a cleavable ADC linker
- Used in the synthesis of PROTACs
- Applied in the synthesis of antibody-drug conjugates (ADCs)
- Enables selective protein degradation via the ubiquitin-proteasome system (for PROTACs)
- Targets cleavable linkers and PEGs (in vitro)
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