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Bio X Cell InVivoMAb anti-mouse IL-4 Antibody, Clone 11B11, Rat IgG1
Supplier: Bio X Cell BE0045R001MG
This monoclonal antibody targets mouse IL-4 (interleukin-4), a 14 kDa cytokine primarily expressed by activated Th2 cells and NK cells. It functions by signaling through the IL-4Rα, stimulating B and T lymphocyte proliferation and differentiation of B cells into plasma cells. The antibody also induces B cell class switching to IgE and up-regulates MHC class II production, while decreasing the production of Th1 cells, macrophages, IFNγ, and dendritic cell IL-12. This antibody neutralizes the bioactivity of natural or recombinant IL-4.
- Reacts with mouse IL-4.
- Neutralizes bioactivity of natural or recombinant IL-4.
- Suitable for in vivo functional studies, neutralization, and IL-4 receptor stimulation.
- Compatible with flow cytometry and western blot applications.
- High purity (≥95%).
- Low endotoxin (≤1EU/mg).
- Produced in an animal-free facility.
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