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Bio X Cell Monoclonal Antibody, 3H3 Clone, Anti-mouse 4-1BB (CD137)
Supplier: Bio X Cell BE0239R001MG
This 3H3 monoclonal antibody targets mouse 4-1BB (CD137), a TNF receptor superfamily member expressed on various immune cells. It provides costimulatory signals to T cells upon ligand binding. The antibody is an agonistic type, known to stimulate 4-1BB signaling in vivo, which is relevant for inducing T cell-mediated antitumor immunity.
- Agonistic antibody, stimulates 4-1BB signaling in vivo
- Reacts with mouse 4-1BB
- Clone 3H3
- Isotype is rat IgG2a
- Immunogen: mouse CD137 human Fc fusion protein
- Applications include in vivo and in vitro 4-1BB stimulation, and in vitro organoids/organ-on-chip
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1EU/mg
- Purity: ≥95%
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
- Storage at 4°C; do not freeze
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