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Bio X Cell InVivoMAb anti-mouse FasL (CD178), Clone MFL3, Unconjugated
Supplier: Bio X Cell BE0319R050MG
The MFL3 monoclonal antibody targets mouse Fas Ligand (FasL), also known as CD178, CD95 Ligand, and TNFSF6. FasL is a 40 kDa type II transmembrane glycoprotein expressed on activated T cells, spleen, testis, and eye. This antibody is reported to block CD178/CD95 induced apoptosis, which typically induces apoptotic cell death to maintain peripheral tolerance. It is produced in an animal-free facility.
- Clone: MFL3
- Host: Armenian hamster
- Reactivity: Mouse
- Isotype: Armenian hamster IgG
- Conjugation: Unconjugated
- Reported applications: In vivo/in vitro FasL blockade, functional assay, IHC (paraffin), flow cytometry
- Formulation: PBS, pH 7.0, no stabilizers or preservatives
- Endotoxin: ≤1 EU/mg
- Purity: ≥95% by SDS-PAGE
- Sterility: 0.2 μm filtration
- Molecular weight: 150 kDa
- Storage: 4°C, do not freeze
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