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Medchemexpress LLC Magnolol | 528-43-8 | 99.8% | 266.33 | 100 MG
SDP

Supplier:  Medchemexpress LLC HYN0163100MG

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Magnolol is a natural lignan isolated from the stem bark of Magnolia officinalis. It acts as a dual agonist for both RXRα and PPARγ. It binds to RXRαLBD and PPARγLBD, inducing transcription of PPRE.

  • Natural lignan isolated from Magnolia officinalis.
  • Dual agonist of RXRα and PPARγ.
  • Binds to RXRαLBD and PPARγLBD in a dose-dependent manner.
  • Induces transcription of PPRE in a dose-dependent manner.
  • Enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells.
  • Attenuates dextran sulfate sodium (DSS)-induced colitis in mice.
  • Decreases DSS-induced proinflammatory cytokines (TNF-α, IL-1β, IL-6).
  • Regulates tryptophan metabolic pathway in mice.

Catalog No. 50-004-27602


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