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Medchemexpress LLC Mal-amide-PEG8-Val-Ala-PAB-PNP | 2210247-59-7 | 95.7% | 1033.08 | C48H68N6O19 | 25 MG
Supplier: Medchemexpress LLC HY14842525MG
Mal-amide-PEG8-Val-Ala-PAB-PNP is a cleavable antibody-drug conjugate (ADC) linker used to attach cytotoxic payloads to antibodies and enable enzymatic release inside target cells. It combines a maleimide reactive group, a PEG8 spacer, a Val-Ala protease-cleavable dipeptide, a para-aminobenzyl self-immolative spacer, and a p-nitrophenyl carbonate leaving group.
- Cleavable by proteases to enable intracellular payload release.
- Maleimide group enables thiol conjugation to antibody cysteines.
- PEG8 spacer improves solubility and linker flexibility.
- High purity suitable for research bioconjugation (~95.7%).
- Available in small mg-scale packs for laboratory conjugation workflows.
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