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Medchemexpress LLC Mal-amido-PEG4-NHS ester | 756525-99-2 | MFCD11041113 | >98.0% | 513.50 | C22H31N3O11 | 250 MG
Supplier: Medchemexpress LLC 250MGHYW040134
Mal-amido-PEG4-NHS ester is a polyethylene glycol (PEG)-based bifunctional linker combining a maleimide group and an N-hydroxysuccinimide (NHS) ester. It is used in PROTAC synthesis and general bioconjugation to enable orthogonal coupling strategies: the maleimide reacts with thiols, while the NHS ester couples to amines. The short PEG4 spacer improves aqueous solubility and helps minimize steric hindrance during conjugation.
- Bifunctional maleimide and NHS ester for orthogonal conjugation
- PEG4 spacer increases solubility in aqueous media
- Enables thiol-selective and amine-selective coupling reactions
- Well-suited for PROTAC linker assembly and bioconjugation workflows
- Supplied with analytical documentation for research use
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