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Medchemexpress LLC Mal-peg2-val-cit-paba-pnp | 1345681-52-8 | 96.8% | 755.73 | C34H41N7O13 | 25 MG
SDP

Supplier:  Medchemexpress LLC HY13115625MG

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Mal-PEG2-Val-Cit-PABA-PNP is a cleavable antibody-drug conjugate (ADC) linker used to attach cytotoxins to antibodies during ADC synthesis. It contains a maleimide reactive group for thiol conjugation, a PEG2 spacer to improve solubility, a cathepsin-cleavable valine-citrulline dipeptide, and a self-immolative p-aminobenzyl spacer with a p-nitrophenyl leaving group.

  • Cleavable linker for antibody-drug conjugate synthesis.
  • Maleimide functional group enables thiol reactivity.
  • Peg2 spacer increases aqueous solubility and hydrophilicity.
  • Val-Cit dipeptide is cleavable by lysosomal proteases.
  • PABA self-immolative spacer allows efficient payload release.
  • PNP leaving group facilitates conjugation chemistry.
  • Available in multiple small-scale pack sizes for research use.
  • Store protected from light and under inert gas for stability.

Catalog No. 50-002-02027


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