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Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-OH | 2055041-39-7 | MFCD29918232 | 96.9% | 706.78 g/mol | C33H50N6O11 | 50 MG
Supplier: Medchemexpress LLC HY14014350MG
Mal-PEG4-Val-Cit-PAB-OH is a cleavable four-unit polyethylene glycol (PEG) linker used to connect an antibody and a cytotoxic payload in antibody-drug conjugate (ADC) synthesis. It contains a maleimide reactive group for thiol coupling, a PEG4 spacer, a Val-Cit protease-cleavable dipeptide, and a para-aminobenzyl (PAB) self-immolative spacer that enables intracellular release of payloads.
- Cleavable four-unit PEG linker enabling protease-mediated release.
- Maleimide functional group for thiol conjugation.
- Val-Cit dipeptide designed for cathepsin B cleavage.
- PAB self-immolative spacer to promote efficient payload release.
- Suitable for ADC synthesis and bioconjugation workflows.
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