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Sigma Aldrich Fine Chemicals Biosciences Malate Dehydrogenase Assay
Supplier: Sigma Aldrich Fine Chemicals Biosciences MAK1961KT

Malate dehydrogenase (MDH EC 1.1.1.37) is an NAD oxidoreductase that catalyzes the NAD/NADH-dependent interconversion of malate and oxalacetate. This reaction is critical to maintain the malate/aspartate shuttle across the mitochondrial membrane and Krebs tricarboxylic acid cycle in the mitochondrial matrix. Increased MDH activity has been observed in neurodegenerative diseases such as Alzheimers disease.
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