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Medchemexpress LLC Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate | 159857-81-5 | MFCD22200431 | 98.7% | 737.76 g/mol | C35H43N7O11 | 500 MG
Supplier: Medchemexpress LLC HY20336500MG
Mc-Val-Cit-PABC-PNP is a cathepsin-cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It couples an antibody-reactive maleimidocaproyl moiety to a valine-citrulline dipeptide cleavage site with a p-aminobenzyl alcohol self-immolative spacer and a p-nitrophenyl carbonate leaving group for payload attachment.
- Cathepsin-cleavable valine-citrulline linker for controlled payload release.
- Maleimidocaproyl functional group enables thiol-selective antibody conjugation.
- P-aminobenzyl alcohol spacer supports self-immolation after cleavage.
- P-nitrophenyl carbonate leaving group facilitates payload coupling.
- High purity suitable for research-grade ADC synthesis.
- Available as a 500 MG package for preparative work.
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