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Apexbio Technology LLC Manidipine 2HCl 89226-75-5 200mg
Supplier: Apexbio Technology LLC B1419200
Manidipine 2HCl (CAS 89226-75-5) is a dihydropyridine-derived small molecule that functions as a calcium channel blocker It selectively inhibits L-type voltage-gated Ca2 channels impeding calcium influx across cell membranes Manidipine 2HCl demonstrates potent inhibitory activity with an IC50 value of 2 6 nM for Ca2 current reduction This compound is utilized in biomedical research to investigate the physiological and pharmacological roles of calcium signaling particularly in cardiovascular and smooth muscle cell function and to explore mechanisms related to calcium-dependent processes
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