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Medchemexpress LLC Maprotiline (hydrochloride) | 10347-81-6 | 99.9% | 500 MG
Supplier: Medchemexpress LLC HYB0444500MG
Maprotiline hydrochloride is a highly selective noradrenergic reuptake inhibitor with strong antidepressant, antitumor, and neuropathic pain-relieving effects, exhibiting oral activity. This compound induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1.
- Induces cell apoptosis and inhibits cell viability in a dose- and time-dependent manner.
- Inhibits metastasis and restrains migration of liver cancer cells.
- Affects the ERK pathway and inhibits SREBP2 phosphorylation.
- Targets CRABP1 and regulates cholesterol biosynthesis.
- Effectively reduces neuropathic pain in mice.
- Inhibits liver cancer tumor growth in vivo.
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